Andrew Bayliffe, Chief Scientific Officer of Marengo Therapeutics and a director of the company’s board, has 25 years of leadership experience in the biopharmaceutical industry, with expertise in the discovery and development of both small molecule and antibody therapeutics across a broad range of diseases areas. He held senior roles in antibody discovery and development in the US and UK and worked on early anti-CD3 antibodies, other immune engagers, and TCR-based therapeutics. Most recently, at GlaxoSmithKline (GSK), he served as head of the Fibrosis and Lung Injury Discovery Unit at GSK’s R&D headquarters in Stevenage, UK.

Andrew is a venture partner at ATP (Apple Tree Partners) and an honorary professor at the Wolfson Institute of Experimental Medicine at Queens College in Belfast. He completed his undergraduate and PhD studies in pharmacology, physiology, and molecular biology at Manchester University and Leeds University in the UK.

As Vice President, Head of Discovery for Marengo Therapeutics, Madan Katragadda leads the group responsible for discovering, designing, and delivering biotherapeutic candidates with optimal biophysical and manufacturable properties. He has more than 15 years of experience discovering and developing a wide range of biotherapeutic modalities spanning peptides, fusion proteins, antibody-drug-conjugates, and multi-specific antibodies. His first foray into biotherapeutics started with the discovery of peptide-based complement inhibitors during his postdoc tenure at the University of Pennsylvania. His work led to out-licensing of an anti-C3 peptide to Apellis pharmaceuticals, who are currently testing it in several inflammatory diseases. At Pfizer, Madan led an Antibody Engineering group, built cross-functional teams to deliver on innovative ideas and new technology platforms and managed several biotherapeutic projects through internal and external collaborations. He delivered several biotherapeutic candidates to treat Inflammatory and oncology indications for preclinical/clinical development. His work at the University of Pennsylvania and Pfizer resulted in several patents and publications.

Madan holds a Ph.D. in biochemistry from the University of Connecticut and completed his postdoctoral training at the University of Pennsylvania.

As Head of Human Resources, Kelly Capra brings over 25 years of broad HR experience, building organizations for growth while fostering an engaging culture and a positive employee experience. Working at both the strategic and hands-on level, Kelly is well versed in all aspects of HR with an emphasis on talent acquisition and development, employee engagement, culture building and change management. Kelly serves as Founder & President of her own consultancy, BUILD HR Consulting & Coaching, leading a team to collaborate with startups and mid-size companies to build their HR capability. Prior to this, she also served as the Vice President of HR for Berg Health and as HR Executive for Repligen, where she worked with the CEO and senior leadership to implement people strategies, enabling the company to grow quickly and the organization to scale, nearly doubling the size of the company in two years.

Kelly earned her MS in Human Resource Management from Lesley University, her BS degree in Social Science from Michigan State University, and a Graduate Certificate in Executive Coaching from William James College. She is currently pursuing a Masters in Human Development and a PhD in Organizational Development & Change with Fielding Graduate University.

As Vice President, Head of Immunology for Marengo Therapeutics, Jacques Moisan leads the group responsible for preclinical pharmacology testing of biotherapeutic candidates to help understand optimal design and key mechanistic insight into the unique T cell activation profile of Marengo’s novel STAR platform. He brings 14 years of experience in the biopharmaceutical industry to Marengo, overseeing teams driving concept through molecule screening and regulatory filing. Starting his career at AstraZeneca developing biologics for rheumatological indications, he soon made the transition to the immune-oncology field helping to build and shape multiple checkpoint inhibitor programs as well as T cell agonist approaches. Jacques then joined Lycera, a biotech company developing oral small molecule RORgamma agonists which was part of an exclusive global collaboration agreement with Celgene in 2015. Joining EMD Serono in 2016, Jacques contributed to shape the immune-oncology pipeline and team growth with increasing responsibility finishing with accountability for the T and NK discovery space within the Oncology/Immuno-oncology research department. Throughout his tenure at EMD Serono, he oversaw multiple IND filings and also authorship on numerous patents and publications.

Jacques holds a Ph.D. in Experimental Medicine from McGill University and completed his postdoctoral training at the Brigham and Women’s Hospital with affiliation to Harvard Medical School.

As Head of Clinical Operations for Marengo Therapeutics, Alyssa Marino is responsible for building the operational foundation of the Clinical Development Organization and delivering pioneering study execution methods. Alyssa brings over two decades of experience overseeing the execution of multiple clinical programs in early oncology. She has held several roles of increasing responsibility with companies such as Organogenesis, Sanofi-Genzyme, Novartis, Merck-Serono, and H3 Biomedicine, where she directed several clinical operations groups and mentored those new to clinical development operations, ensuring that work in clinical research could reach new heights. Alyssa’s passion is advancing early drug candidates into the clinic within a quality framework, bringing us one step closer to helping more patients beat cancer.

Alyssa holds a BA from Boston College and CCRA from the Association of Clinical Research Professionals.

As Senior Strategic Advisor to Marengo Therapeutics, Dr. Chabner brings decades of extensive experience pioneering key research in the field of cancer drug discovery and development. In addition to his role at Marengo, he is an Allen Distinguished Investigator, Clinical Director Emeritus for the Massachusetts General Hospital Cancer Center, and a Professor of Medicine at Harvard Medical School. During his career at the National Cancer Institute, he served as a Senior Investigator in the Laboratory of Chemical Pharmacology, Chief of the Clinical Pharmacology Branch, Director of the Clinical Oncology Program, and Director of the Division of Cancer Treatment. At the NCI, he maintained an active laboratory program in cancer pharmacology, where he led the development of the breast cancer drug Taxol. His research contributed significantly to the development of high dose chemotherapy regimens, and to standard therapies for lymphoma. Dr. Chabner is a senior editor for The Oncologist and in 2006, he received a presidential appointment to the National Cancer Advisory Board at the NCI.

Dr. Chabner received his M.D. from Harvard Medical School.

Dr. E. John Wherry is the Chair of the Department of Systems Pharmacology and Translational Therapeutics in the Perelman School of Medicine, Director of the UPenn Institute for Immunology, and the Barbara and Richard Schiffrin President’s Distinguished Professor. He has helped pioneer the field of T cell exhaustion, assisting in identifying the role of the “checkpoint” molecule PD-1 and others for reinvigoration of exhausted T cells in cancer and defining the underlying molecular and epigenetic mechanisms of exhausted T cells. He has received numerous honors in his career, including the Distinguished Alumni award from the Thomas Jefferson University, the Cancer Research Institute’s Frederick W. Alt Award for New Discoveries in Immunology, and the Stanley N. Cohen Biomedical Research Award from the University of Pennsylvania Perelman School of Medicine. Dr. Wherry received his PhD from Thomas Jefferson University.

Dr. James Gulley brings over 20 years of leadership experience in the oncology field, serving currently as Co-Director of the newly formed Center for Immuno-Oncology (CIO) at the National Cancer Institute (NCI), part of the National Institutes of Health. The work he oversees at the CIO concentrates on focusing the immune response through vaccines or adoptive cellular therapy for solid tumors. He was instrumental in the clinical development of multiple vaccines including PROSTVAC, from the first-in-human studies at the CCR through a completed phase 3 clinical trial.  He currently oversees new efforts in synthetic biology with cell therapy-based approaches including TCR engineered T-cells, CAR-T cells and engineered NK cells. Dr. Gulley has been the recipient of many honors and awards; most recently including the Hubert H. Humphrey Award for Service to America, the Award NCI Director’s Group Award, and the SITC Collaborator Award. He earned his PhD and MD at Loma Linda University. He completed his residency in Internal Medicine at Emory University, followed by a fellowship in Medical Oncology at the National Cancer Institute.

Dr. Lillian Siu has over 20 years of experience as a senior medical oncologist at Princess Margaret Cancer Centre, as well as experience as a Professor of Medicine at the University of Toronto. Dr. Siu’s main research focus is in precision oncology, biomarkers especially circulating tumor DNA and clinical trials methodology. She is the Director of the Phase I Program, Co-Director of the Bras and Family Drug Development Program, and Clinical Lead for the Tumor Immunotherapy Program at Princess Margaret Cancer Centre. Dr. Siu is currently the Editor-in-Chief for American Association for Cancer Research’s newest journal Cancer Research Communications. She is also a scientific editor for Cancer Discovery and is on the editorial board for JAMA Oncology, Cell and Cancer Cell. Dr. Siu earned her MD from the University of Toronto.

Dr. Howard Kaufman has over 25 years of experience in cancer immunotherapy and drug development. Previously, he served as a Society for Immunotherapy of Cancer (SITC) President and is currently the President and Chief Executive Officer at Ankyra Therapeutics. In addition, he served as a Clinical Associate at Massachusetts General Hospital. His research focuses on developing oncolytic viruses and immunotherapy for the treatment of melanoma and other cutaneous malignancies. His work has led to the FDA approval of the first oncolytic virus in cancer treatment, and established the importance of anti-PD-L1 treatment for advanced Merkel cell carcinoma. His lab continues to advance our understanding of how viruses induce immunogenic cell death and initiate host anti-tumor immunity. Dr. Kaufman earned his MD from Loyola University Chicago.